Clinical Field Trial to Evaluate the Efficacy of Topically Applied Diclofenac Liposomal Cream for the Relief of Joint Lameness in Horses

Topical application of diclofenac liposomal cream over specific painful joint areas reduces pain and lameness when compared with placebo in a blinded study. Topical application is more convenient for lay person application and is likely to reduce the risk of toxicity and adverse effects typically associated with nonsteroidal anti-inflammatory drugs. Authors’ addresses: Alpine Animal Hospital, 17776 Highway 82, Carbondale, CO 81623 (Bertone); IDEXX Pharmaceuticals, Inc., 4249–105 Piedmont Parkway, Greensboro, NC 27410 (Lynn, Hepler); and Bradford Park Veterinary Hospital, 1255 E. Independence Street, Springfield, MO 65804 (Sifferman). Dr. Vatistas is deceased. His former address was 7650 Olivas Lane, Vacaville, CA 95688.Dr. Kelch’s present address is 1316 Beacon Hill Lane, Knoxville, TN 37919. © 2002 AAEP.